$SYRE

Spyre Therapeutics (SYRE) Insider Trading

Spyre Therapeutics, Inc.Mid Cap$8.7B

Spyre Therapeutics insiders sold $443.0M in the last 12 months, led by Fairmount Funds Management, with no insider purchases.

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Insiders (12-Month)

7 Insiders

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Insider Buys (12-Month)

No insider buys

Latest Buy

No open-market buys on record

Politicians (12-Month)

No politician trades

Recent Insider Trades in SYRE

TypeInsiderRolePriceSharesΔOwnValueFiled
SELLOE+Sale10b5-1
King-Jones HeidyOfficer$91.0328,933−91.0%-$2,633,902Oct 3, '26
SELLOE+Sale10b5-1
Burrows Scott LCFO$90.4725,000−23.9%-$2,261,831Oct 3, '26
SELL10b5-1
Turtle CameronCEO$92.0115,000−2.7%-$1,380,105Oct 2, '26
SELLOE+Sale10b5-1
King-Jones HeidyOfficer$87.3528,399−90.9%-$2,480,529Sep 4, '26
SELLOE+Sale10b5-1
Burrows Scott LCFO$88.7525,732−24.4%-$2,283,821Sep 4, '26
SELL10b5-1
Turtle CameronCEO$87.2915,000−2.6%-$1,309,410Sep 4, '26
SELLOE+Sale10b5-1
Albers Jeffrey W.Director$104.5323,000−71.1%-$2,404,190Aug 11, '26
SELLOE+Sale
Burrows Scott LCFO$95.577,500−7.1%-$716,771Aug 5, '26
SELL10b5-1
Turtle CameronCEO$95.5115,000−2.6%-$1,432,705Aug 5, '26
SELLOE+Sale10b5-1
Burrows Scott LCFO$87.747,500−7.1%-$658,040Jul 3, '26
SELLOE+Sale10b5-1
Sloan SheldonCMO$87.708,334All-$730,896Jul 3, '26
SELL10b5-1
Turtle CameronCEO$87.6915,000−2.5%-$1,315,346Jul 3, '26
SELLOE+Sale
Burrows Scott LCFO$87.1315,000−13.3%-$1,307,000Jun 27, '26
SELL10b5-1
Henderson Michael ThomasDirector$100.0020,000−22.6%-$2,000,000Jun 24, '26
SELL
Fairmount Funds Management LLCDirector$85.314,684,781−85.2%-$399,658,667Jun 23, '26
SELLOE+Sale10b5-1
Sloan SheldonCMO$75.008,333All-$624,975Jun 4, '26
SELL10b5-1
Turtle CameronCEO$70.4315,000−2.4%-$1,056,486Jun 4, '26
SELLOE+Sale10b5-1
Burrows Scott LCFO$71.067,500−7.1%-$532,937Jun 4, '26
SELL10b5-1
Henderson Michael ThomasDirector$74.4080,000−47.4%-$5,952,050May 9, '26
SELLOE+Sale10b5-1
Burrows Scott LCFO$71.3712,500−11.3%-$892,125May 2, '26
SELLOE+Sale10b5-1
Sloan SheldonCMO$71.5078,333All-$5,600,701May 2, '26
SELL10b5-1
Turtle CameronCEO$71.3715,000−2.4%-$1,070,507May 2, '26
SELL10b5-1
Turtle CameronCEO$49.3315,000−2.3%-$739,912Apr 4, '26
SELLOE+Sale10b5-1
Sloan SheldonCMO$50.007,958All-$397,900Apr 4, '26
SELLOE+Sale10b5-1
Burrows Scott LCFO$49.347,500−7.1%-$370,076Apr 4, '26
SELL10b5-1
Turtle CameronCEO$42.1915,000−2.3%-$632,866Mar 4, '26
SELLOE+Sale10b5-1
Burrows Scott LCFO$40.652,500−2.5%-$101,620Mar 3, '26
SELL10b5-1
Turtle CameronCEO$32.8015,000−2.2%-$492,045Feb 5, '26
SELL10b5-1
Turtle CameronCEO$30.6815,000−2.2%-$460,134Jan 6, '26
SELL10b5-1
Turtle CameronCEO$29.0215,000−2.1%-$435,356Dec 4, '25
SELL10b5-1
Turtle CameronCEO$23.3345,000−6.0%-$1,049,778Nov 6, '25
Older than 12 months
SELL
Burrows Scott LCFO$16.2618,428−15.8%-$299,639Sep 3, '25